Biostat 580B - Statistical Genetics Seminar
1 credit: Entry codes available from Elizabeth Thompson
Spring Quarter 1998
Seminar: Tuesday 4:00-5:00 C301 Padelford
In reading, discussing, and presenting the papers, remember the seven
important questions:
Why? What? Why? How? Why? What next? and WHY?
Schedule:
March 31: Sharon Browning
Boehnke M and NJ Cox (1997)
Accurate Inference of Relationships in Sib-Pair Linkage Studies.
Am J Hum Genet 61:423-429.
Copies are available in the usual Stat and Biostat boxes/folders.
April 7: Elizabeth Thompson
Realizing the history of an allele; implications for disequilibrium mapping.
Thompson EA and Neel JV (1997)
Allelic disequilibrium and allele frequency distribution as a function of
social and demographic history.
Am J Hum Genet 61:197-204.
Reprints will be available at the seminar, March 31.
April 14: Jinko Graham
Disequilibrium mapping for fine-scale mapping of a rare allele.
Preprint will be available April 7.
April 21: No seminar See Sam Karlin's seminar, below.
April 28: Nicky Chapman
B. Rannala and M. Slatkin, (1998)
Likelihood analysis of disequilibrium mapping, and related problems
Am J Hum Genet, 62, 459--473.
Unfortunately Monty Slatkin will not be visiting this quarter, but
Nicky has volunteered to explain his version of disequilibrium mapping.
Paper is available in statgen mailbox.
May 5: Katrina Goddard (Ellen advising)
L. Almasy and J. Blangero, (1998)
Multipoint quantitative trait linkage analysis in general pedigrees
Am J Hum Genet, 62, 1198--1211.
Paper is available in statgen mailbox.
May 12: Greg Snow (Joe advising)
L. Lazzeroni (1998)
Linkage disequilibrium and gene mapping: an empirical
least-squares approach.
Am J Hum Genet, 62, 159--170.
May 19: Joe Felsenstein
Coalescent likelihoods and linkage disequilibrium mapping.
A background paper is
Likelihoods on coalescents: a Monte Carlo sampling approach to inferring
parameters from population samples of molecular data
by
Joseph Felsenstein, Mary K. Kuhner, Jon Yamato, and Peter Beerli
It is available by ftp as statgen/seillier.ps at
evolution.genetics.washington.edu
May 26: Michael Levitz
Lybrand, T. P. (1995)
Ligand-protein docking and rational drug design
Current Opinion in Structural Biology, 5: 224--228.
Sobolev, V., et al. (1998)
CASP2 Molecular Docking Predictions with the LIGIN Software,
PROTEINS: Structure, Function and Genetics, Suppl. 1: 210--214 (1997).
Papers (even-numbered pages only) in stat and also biostat StatGen box/folders.
June 2: Beatrix Jones
Whittemore, A.S., and Tu, I-P. (1998)
Simple, robust linkage tests for affected sibs,
Am J Hum Genet, 62: 1228--1242.
Paper in Statgen mailbox in Stat -- I have copy for Biostat
-- someone please remember to ask me for it.
Other seminars:
All should attend these talks, if they can.
April 8: Michael Boehnke: Wed 1:30-2:30, Room T-747
April 17: Duncan Thomas: Fri 3.30 -4.30, Room T-733
NOTE CHANGE
April 20: Sam Karlin Mon. (NOT Wed) 4.00 p.m. Room D-209
April 21: Sam Karlin Tues. (NOT Wed) 4.00 p.m. Room D-209
May 28; Jinko Graham Thurs. 3.30 p.m.; Biostat Dept Seminar
June 1; Dick Karp Monday 3.30 p.m.; Stat Dept Seminar
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